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Product Code: ADB-BUTINACA
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IUPAC Name: 1-butyl-N-(1-carbamoyl-2,2-dimethyl-propyl)indazole-3- carboxamide.

ADB BUTINACA (ADBB) is a synthetic cannabinoid. It is new to the market and is legal almost all over the world. Its effect is not inferior to such well-known cannabinoids as 5F-MDMB-2201, 5F-MDMB-PINACA (5F-ADB), 5-CL-ADB-A.

It is a potent agonist of the CB1 receptor and CB2 receptor with EC50 values ​​of 0.52 nM and 0.88 nM.


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ADB-BINACA
ADB-BINACA structure.png
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC21H24N4O2
Molar mass364.449 g·mol−1
3D model (JSmol)

ADB-BINACA is a cannabinoid designer drug that has been found as an ingredient in some synthetic cannabis products.[1] It was originally developed by Pfizer as a potential analgesic, and is a potent agonist of the CB1 receptor with a binding affinity (Ki) of 0.33 nM and an EC50 of 14.7 nM.[2]

ADB-BUTINACA[edit]

ADB-BUTINACA
ADB-BUTINACA structure.png
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC18H26N4O2
Molar mass330.432 g·mol−1
3D model (JSmol)

The analogue with a 1-butyl substitution on the indazole ring rather than 1-benzyl has also been sold as a designer drug under the name ADB-BINACA, but is now more commonly referred to as ADB-BUTINACA to avoid confusion with the benzyl compound.[3][4][5][6][7] It is a similarly potent CB1 agonist, with an EC50 of 6.36 nM.[8][9]

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